==== A) Blood samples ====

Labs:\\ 
1. Ullevål Hospital, Department of Medical Biochemistry. Tubes destroyed after 7 days.\\ 
2. Aker Hospital, Hormone Lab. Tube destroyed after 1 year.\\
3. St. Olavs hospital, Trondheim: Department of Clinical Pharmacology. Serume from St. Olavs are returned to Norment. Stored in biobank.\\
Contact person Norment: Nils Eiel Steen

Biobank
From EDTA tubes: DNA and plasma extracted the same day or next day after sampling, and then stored in -80 freezer. One tube of full blood is also stored.\\ 
From RNA Tempus tube: RNA extracted by the genetics group at Ullevål.\\
DNA deep sequenzing analysis: Spesific consent form. All healthy controls and some patients are asked.\\
Contact person: Srdjan Djurovic.

==== B) Urine samples ====

1) On the day of neuro cognitive testing: One tube sent to St. Olavs for drug screening. One tube stored at biobank for cortisol analysis.\\
2) On MRI day: One tube sent to St. Olavs for drug screening.\\
Contact person: Nils Eiel Steen

==== C) Hair samples ====

For cortisol analysis. All participants asked. Included in the consent form for the TOP project.\\
Contact person: Monica Aas and Nils Eiel Steen

==== D) Stemcells - Skin biopsy ====

Patients and controls. Sampled for elected participants in both groups since 2014. Now working on changing methods to blood sampling instead of skin biopsy.\\ 
Contact person: Srdjan Djurovic 



==== E) Other data sampling at lab ====

Patients: Daily medication. Fasting.\\
Healthy Controls: Daily medication and diet supplies. Fasting. Short physical exam: Blood pressure, pulse, height, weight, waist and hip measures. Nicotine use.\\
All data sent to TSD the day of sampling.\\
Contact person: Thomas Bjella



=== Links to other relevant documents: ===



-	Details of analyses in blood: https://www.med.uio.no/norment/english/internal/protocols/lab/dokumenter/14022017_analyses-and-labs_-top-blood-protocol_norwegian-and-english.pdf

-	Methods used for analyses in blood: https://www.med.uio.no/norment/english/internal/protocols/lab/dokumenter/biochemical-and-hormonal-analyses-of-blood-samples-method-changes---oct-2020.pdf


Responsible for this wiki-page: Line Gundersen


==== Relevant data locations on TSD ====

<code>
/tsd/p33/data/durable/groups/biostats/molgen/GeneExpression_Microarray/TOPtot_20210223/
</code>
