====== Cohort overview ====== 


NORMENT is managing genotypes from multiple different studies/cohorts. The main studies are

  * **TOP and NORSMI**
    * TOP study is the core sample at NORMENT, and is combined with the national network (**NO**rwegian **R**esarch Network in **S**evere **M**ental **I**llness).
    * Includes the schizophrenia, bipolar, severe depression with detailed phenotypes (TOP study) and samples across Norway with less phenotyping (NORSMI) 
  * **BUPgen** (**B**arne- og **U**ngdoms**P**sykiatri, **gen**etikk)
    * National Network for neurodevelopmental disorders
    * Includes a variaty of diagnosis, ADHD, ASD, Tourette syndrome, Hypersomnia, clinical phenotypes
  * **NeuroMRI CF**
    * NeuroImaging Core facility
    * Brain scans from routine clinic - "broad consent"
  * **DemGene**
    * **Dem**entia **Gene**tics: National Network for dementia, cognitive disorder and genetics
  * **MoBa**
    * The Norwegian Mother, Father and Child study (**Mo**r og **Ba**rn-undersøkelsen)
    * Cohort study of 100000 children and 140 000 parents, prospective birth cohort
  * **Blodbank**
    * Genotyped healthy blood donors. No phenotype information.
  * **Others**
    * ...


**Number of genotyped individuals per study/cohort, organised by phenotype, is given in this google doc [[https://docs.google.com/spreadsheets/d/1DAc4nXQmLNjB4yedTZC0hB_EgtMW90n9MM8K9lY7cng/edit#gid=0|spreadsheet]].**




===== TOP (including NORSMI) =====

**T**hematically **O**rganized **P**sychosis research

Dataset contains:

^ Diagnosis           ^  #   ^ 
| Schizophrenia (SCZ)  | 800  |
| Bipolar (BP)        | 470  |
| Other (MD/NOS)      | 270  |
| Controls            | 1000 | 

Contact persons:
  * Thomas Bjella (database) <thomas.bjella@medisin.uio.no>
  * Lavinia Athanasiu (Genetics) <lavinia.athanasiu@medisin.uio.no>
  * Ole A. Andreassen (PI) <o.a.andreassen@medisin.uio.no>

More info at the [[http://www.med.uio.no/norment/forskning/prosjekter/|official webpage]].

===== BRAIN =====

**B**ipolar **R**esearch **a**nd **I**nnovation **N**etwork

Norwegian regional cohorts
  * Bipolar spectrum disorders'

^ Diagnosis                 ^ #   ^
| Bipolar (BPI,BPII,BP NOS) | 800 |

Contact persons:
  * Gunnar Morken <gunnar.morken@ntnu.no>
  * Ole A. Andreassen (PI) <o.a.andreassen@medisin.uio.no>
  * Lavinia Athanasiu (Genetics) <lavinia.athanasiu@medisin.uio.no>
  * Thomas Bjella (Database) <thomas.bjella@medisin.uio.no>

===== BUPgen =====

Contact persons:
  * Terje Nærland (Managing director) <ternae@ous-hf.no>
  * Ole A. Andreassen (PI) <o.a.andreassen@medisin.uio.no>
  * Lavinia Athanasiu (Genetics) <lavinia.athanasiu@medisin.uio.no>
  * Liliana Buer (Database) <lilianabuer@gmail.com>

More info at the [[http://www.nevsom.no/index.asp?id=50809|official webpage ]].

Current in-house ID-list [[https://www.med.uio.no/norment/english/internal/protocols/database/index.html]].


===== DemGene =====

A collection of genotyped data from a number of different cohorts.

Contact persons;
  * PI Ole A. Andreassen - <ole.andreassen@medisin.uio.no>
  * Lavinia Athanasiu (genetics and overview) - <lavinia.athanasiu@medisin.uio.no>
 
Cohorts:
  * **HUKLI** Register for personer som utredes ved hukommelsesklinikker ved sykehus i Helse Sør-Øst og Helse Vest 
  * **PADR study** (Prodromal?) Alzheimer and MCI (Mild Cognitive Impairment) with depression.
  * **SESAM biobank** Stavanger Parkinson prosjekt
  * **TrønderBrain**
  * **HUNT** Genetikk ved demens i Nord-Trønderske populasjoner
  * **DDI** Nasjonalt initiativ for utvikling av tidlig demensdiagnostikk
  * Demensstudien i Nord-Norge/demens i distriktshelsetjenesten
  * **DEMVEST** Demensstudien på Vestlandet DEMVEST

Controls are specific to Dementia.

===== MoBa =====

MoBa Psychiatric genetics
  * PI Ole A. Andreassen  - <ole.andreassen@medisin.uio.no>
  * co-PI Ted Reichborn-Kjennerud  - <Ted.Reichborn-Kjennerud@fhi.no>
  * Coordination Helga Ask  - <Helga.Ask@fhi.no> 
  * Data analysis Kevin O`Connell  - <kevin.oconnell@medisin.uio.no>
  * Genotype data Lavinia Athanasiu  - <lavinia.athanasiu@medisin.uio.no>
  * Data base Thomas Bjella  - <thomas.bjella@medisin.uio.no>
  * Liason Martin Tesli  - <MartinSteen.Tesli@fhi.no>

More info at the [[https://www.fhi.no/studier/moba/|official webpage ]].

===== Blood Donor Cohort =====

Genotyped blood donors. Can be used as controls. Age ranges between 18-60 years. 
Gender information is not collected for the blood donor data (gender is inferred from the data).